Aurora, Colorado 80045


Purpose:

This study plans to learn more about a new test to look at liver function, the HepQuant-Shunt (HQ-Shunt). The HQ-Shunt is being evaluated for safety and effectiveness as an alternative to Hepatic Venous Pressure Gradient testing in patients with liver disease.


Study summary:

The goal of this study is to demonstrate the HQ-SHUNT is safe, simple to administer, noninvasive, cost-effective, and well tolerated by patients. This study will compare the HQ-SHUNT to Hepatic Venous Pressure Gradient (HVPG) testing. In this study, 100 consecutive patients with various etiologies of liver disease who have undergone technically successful HVPG testing as standard of care will also undergo HQ-SHUNT testing.


Criteria:

Inclusion Criteria: - Liver disease patient scheduled to have an Hepatic Venous Pressure Gradient (HVPG) procedure - At time of enrollment, being between the ages of 18 and 75 Exclusion Criteria: - Concomitant treatment with both a beta blocker and an ACE inhibitor - Concurrent hepatic malignancy. Patients with a history of treated HCC can be included if there is no evidence of recurrent disease at the time of this study. - Unstable angina or history of myocardial infarction or congestive heart failure within 6 months prior to enrollment into this study - Renal insufficiency with chronic kidney disease stage 4 or 5 (GFR < 30 mL/min/1.73m2) - Crohn's disease or any active intestinal inflammatory condition - Having had an ileal resection - Diabetic Gastroparesis - Pregnancy or intent to become pregnant. Urine pregnancy tests will be performed prior to HQ SHUNT testing. - Inability to consent for one's self


NCT ID:

NCT02523196


Primary Contact:

Principal Investigator
Amanda Wieland, MD
University of Colorado, Denver

Jennifer DeSanto, RN
Phone: 303-724-1861
Email: jennifer.desanto@ucdenver.edu


Backup Contact:

Email: stephanie.hill@ucdenver.edu
Stephanie Hill, MA
Phone: 3037241870


Location Contact:

Aurora, Colorado 80045
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 19, 2017

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