Salt Lake City,
The investigators plan to evaluate the length of time to discharge readiness between the
groups (continuous femoral nerve blocks (cFNB) vs. liposomal bupivacaine (LB) vs.
periarticular infusion cocktails (PIC) following primary total knee arthroplasty (TKA). In
addition, the investigators will compare quadriceps strength recovery over time and
exploratory variables between the groups.
- ≥ 40 Years Old
- Scheduled for Primary Total Knee Arthroplasty
- Opiate Tolerant (≥60mg/day oral morphine/equivalent for ≥1 week)
- Neuromuscular deficit affecting the lower limbs
- Peripheral neuropathy
- Known allergy or intolerance to Bupivacaine or Ropivacaine
- Hepatic Disease
- Renal Disease/Patients needing Dialysis
- Planned unicompartmental knee replacement
- Less than 90 degree of knee flexion preoperatively.
- Patients who lack the capacity to consent or are unwilling to do so
- At the discretion of the PI, patients who may have difficulty complying with standard
of care (SOC) followup may also be excluded