This research study is looking at a small device that measures white blood cell (WBC) counts
by being placed against the finger nail for participants who are undergoing stem cell
transplantation at Massachusetts General Hospital or have a hematologic malignancy and are
being seen as an outpatient.
The objective of this study is to obtain data that would support the use of a method to
obtain WBC counts from images of small blood vessels called capillaries. These would be
obtained by pressing a small device on the surface of participants' finger nails to look
through the nail. These images will be obtained using a portable microscope called the
Dino-Lite Digital Microscope.
Having a non-invasive way to quickly measure WBC counts could be useful for a variety of
- Patients with lymphoid malignancies or plasma cell dyscrasias who are admitted to the
Massachusetts General Hospital to undergo autologous stem cell transplantation or are
seen in the outpatient clinic
- Age ≥ 18 years
- Ability to understand and the willingness to sign a written informed consent document.
- Patients must have WBC ≥ 3000 / µl and ANC ≥ 1500 / µl at admission or their last
clinical visit to be enrolled.
- History of allergic reactions attributed to compounds of similar chemical or biologic
composition of baby oil.
- Skin phototype < 4 in the Fitzpatrick scale.