Lebanon, New Hampshire 03766


The primary aim of this project is to conduct a randomized controlled pilot study evaluating the feasibility and potential effectiveness of a newly developed combined Health At Every Size and Acceptance and Commitment Therapy (HAES/ACT) treatment, known as Accept Yourself! compared to a commercial behavioral weight loss program, Weight Watchers (WW). Obese women (BMI ≥ 30) with Major Depressive Disorder will be randomly assigned to one of these two treatments. Depression, physical health, and other psychosocial outcomes will be assessed prior to treatment, at post-treatment, and at 3, 6, 9, and 12-month follow up assessments.


Inclusion Criteria: - English-speaking - Major Depressive Disorder (assessed using the Structured Clinical Interview for DSM-IV, SCID-IV) - Body Mass Index (BMI) greater than or equal to 30 - Not taking medications or on stable medication regimens (i.e. no medication changes for six weeks prior to enrollment or during the study) Exclusion Criteria: - current substance dependence - history of psychotic symptoms - high risk of suicide/self-harm - current enrollment in a weight-loss program - weight loss surgery in the past year - current psychotherapy - inability to postpone weight loss or depression treatment interventions for the duration of the study - taking antipsychotic, tricyclic, or oral corticosteroid medication - unwilling to be randomized to the study treatments



Primary Contact:

Principal Investigator
Margit I Berman, Ph.D
Geisel School of Medicine at Dartmouth

Margit I Berman, Ph.D.
Phone: 603-650-4724
Email: Margit.I.Berman@dartmouth.edu

Backup Contact:

Email: Mark.T.Hegel@hitchcock.org
Mark T Hegel, Ph.D.
Phone: 603-650-6188

Location Contact:

Lebanon, New Hampshire 03766
United States

Margit I Berman, Ph.D.
Phone: 603-650-4724
Email: Margit.I.Berman@dartmouth.edu

Site Status: Recruiting

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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