Scottsdale, Arizona 85259


Purpose:

This study is being done to better understand the relationship between inflammation and insulin resistance in your Adipose (fat) Tissue .


Study summary:

This study is being done to determine whether eosinophils (a type of white blood cell) play an important role in human fat metabolism and inflammation. This study is being done to determine if fish oil supplement could play a role in reducing inflammation and improving insulin sensitivity in your fat tissue.


Criteria:

Lean, healthy person with a body mass index (BMI) of 25 or less, or you are obese, BMI between 30 and 50, and non-diabetic. Lean healthy controls will not be on any medication and will be undergoing elective abdominal surgery excluding those involving acute inflammation (i.e. acute cholecystitis, bowel perforation, or diverticulitis). Obese, non-diabetic subjects will have a BMI between 30 and 50 and be taking no medications affecting glucose metabolism or lipid metabolism. These subjects will be identified from a pool of patients undergoing an elective abdominal surgical procedure such as inguinal hernia repair, laparoscopic Nissen fundoplication, planned cholecystectomy, but also bariatric surgery. Volunteers will not be taking corticosteroid therapy or have a history of asthma, COPD or atopic syndrome. All subjects will undergo a medical history intake and a physical examination followed by an OGTT to confirm normal glucose.


NCT ID:

NCT02378077


Primary Contact:

Principal Investigator
Elena Anna De Filippis, MD, PhD
Mayo Clinic

Charlene Robinson
Phone: 480-301-4626
Email: ARZClinicalStudies@mayo.edu


Backup Contact:

N/A


Location Contact:

Scottsdale, Arizona 85259
United States

Charlene Robinson
Phone: 480-301-4626
Email: ARZClinicalStudies@mayo.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 22, 2017

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

If you would like to be contacted by the clinical trial representative please fill out the form below.