Expired Study
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Gainesville, Florida 32610


Purpose:

The investigators propose to conduct a head-to-head, randomized clinical trial to compare the effectiveness of Minoxidil with Spironolactone and Finasteride in treating postmenopausal females with Androgenetic Alopecia (AGA).


Study summary:

Participants diagnosed with AGA will be randomized into one of the two treatment arms outlined below, and will take the assigned treatment for a total duration of 12 months. Medications will be dispensed by a nurse who is blinded to the participants within each treatment group. Global photograph assessment and participant questionnaires at 0, 4, 8 and 12 months will be the primary means to determine improvement in hair loss. Compare the following interventions in treating postmenopausal female AGA: A) Combination 5% Minoxidil and 200mg Spironolactone (Combination Group) B) 5mg Finasteride with placebo topical preparation (Single Group)


Criteria:

Inclusion Criteria: - female - postmenopausal (>60 years old or with total hysterectomy) - diagnosed with androgenetic alopecia - no chemical processing or changes in hair products throughout the study Exclusion Criteria: - men - premenopausal women (<60 or without hysterectomy) - participants allergic to any of the study medications (minoxidil, finasteride, spironolactone) - participants with other co-existing forms of alopecia (traction, alopecia areata, or scarring alopecias) - participants with obstructive uropathy or advanced liver disease - prior hair loss treatment within the last 6 months - hair loss from the chemotherapy or other medication-induced alopecia - Hair loss for greater than 5 years, as medical therapy is unlikely to have much effect at restoring hair follicles inactive for that long of a period.


NCT ID:

NCT02483195


Primary Contact:

Principal Investigator
Christina L. Mitchell, M.D.
University of Florida


Backup Contact:

N/A


Location Contact:

Gainesville, Florida 32610
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 22, 2017

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