Whole-body periodic acceleration (WBPA) is a new, non-invasive, and promising therapy for a
diverse and growing list of disorders including cardiovascular disease 6. During WBPA,
patients lie in the supine position on a bed that is capable of translating back and forth
parallel to the ground, along the head-to-foot axis of the patient. Thus, this treatment is
best described as a form of "passive exercise." The frequency of the translation (up to 180
cycles/minute; cpm) as well as the distance traveled (2-24mm) by the bed can be adjusted by
the patient or health care professional.
The science behind the therapeutic effects of WBPA still remains largely unknown.
The objective of this study is to determine if WBPA may be used as an effective way to reduce
lactic acid concentrations during recovery after intense exercise more rapidly than
previously established methods.
Each visit Subjects will perform a graded treadmill exercise test. They will rest for 10
minutes. At the end of the rest period, resting vital signs (HR and BP) will be recorded as
well as resting oxygen consumption (VO2). Resting capillary blood sample will be taken and
analyzed by the Accutrend portable lactate analyzer to measure blood lactate levels. The
cardiac and metabolic recordings will be measured by PFT GX machine (Medgraphics Ultima; St.
Paul, Minnesota) that will record VO2, VCO2, RER (respiratory exchange ratio), Ve. Heart Rate
will be monitored by a Polar® HR monitor. This machine is attached to a motorized treadmill
with handrails. Each subject will perform a Modified Bruce Protocol which consists of a
maximum of five 3-minute stages. The criteria set for peak exercise is one of the following:
1) 90% of THR; 2) a plateau of oxygen uptake is indicated; 3) if the subject is unable to
maintain the pace of the treadmill; 4) an RER of over 1.0 and/or 5) a plateau in Ve (3).
Additionally, the American College of Sports Medicine (ACSM) guidelines for terminating
exercise testing will be followed(American College of Sports Medicine).
TIMELINE of PROCEDURES
The following recoveries will be tested on 3 separate days:
Visit 1 The subject will walk at 30-40 % of V02 max for the next 20 minutes on the treadmill
after peak exercise. Blood lactate will be taken at minute 20.
Visit 2 The subject will be taken off the treadmill after a 3 minute walk and placed on the
WBPA bed. The horizontal displacement will be held constant at 14 mm, and cycles/min will be
held constant at 140. There is a footboard where the subjects feet are strapped in while
wearing their own shoes. The platform moves in a repetitive motion from head-to- foot
imparting mild periodic inertial forces in the subject's spinal axis (pGz). Blood lactate
will be taken at minute 20.
The subject will be taken off the treadmill after a 3 minute walk and asked to sit in a chair
for 20 minutes. Blood lactate will be taken at minute 20.
- Athletic Individuals who exercise regularly
- Any implantable devices
- currently taking any medication that would effect blood pressure