This research study is evaluating the usefulness of a placebo (a tablet with no active
ingredients) on fatigue in cancer survivors.
Fatigue can be a problem for some people after cancer treatment. In clinical trials, placebos
(tablets with no active ingredients) have been shown to improve symptoms of some medical
conditions including fatigue. This study is being done to test the usefulness of taking
placebos for improving cancer-related fatigue. In this study, the investigators are testing
whether symptoms of fatigue will improve when people know they are taking a tablet with no
This is a randomized study, which means the participant will be put into one of two groups.
Because no one knows which of the study options is best, the participant will be 'randomized'
into one of the two study groups. Randomization means that the participant will be put into a
group by chance. It is like flipping a coin. Neither the participant nor the research doctor
will choose what group he or she will be in. The participant will have an equal chance of
being placed in each of the groups.
- Cancer survivor, with no evidence of active disease
- ≥18 years of age
- ≥6 months and <10 years post active treatment
- Reports being bothered by fatigue in the past month and has a score of <43 on FACIT-F.
- Able to read and write in English
- Being evaluated or likely to be evaluated for a medical cause of fatigue (e.g.,
anemia, hypothyroidism) during the study. (per provider report)
- Have indications of sleep apnea as assessed by Epworth Sleepiness scale score ≥10.
- Are receiving, or are likely to receive another intervention for the treatment of
fatigue during the study period. (per provider report)