This randomized clinical trial studies aromatherapy and essential oils in improving insomnia
and other symptoms in patients with newly diagnosed acute leukemia. Aromatherapy and
essential oils may help improve insomnia and other complications caused by chemotherapy.
I. Does the addition of aromatherapy by diffusion of essential oils improve insomnia in
newly diagnosed, hospitalized leukemia patients?
I. Does the addition of aromatherapy by diffusion of essential oils improve other common
symptoms in newly diagnosed, hospitalized leukemia patients, including pain, nausea, lack of
appetite, shortness of breath, depression, anxiety and wellbeing? II. Do newly diagnosed,
hospitalized leukemia patients find the use of aromatherapy for symptom management a
OUTLINE: Patients are randomized to 1 of 2 groups.
GROUP I: Patients select between 3 scented essential oils: peppermint, lavender, or
chamomile which is diffused in the hospital room from approximately 9 PM in the evening
until morning during week 1 and placebo intervention using rose water during week 2.
GROUP II: Patients undergo placebo intervention using rose water during week 1 and
aromatherapy and essential oils as in Group I during week 2.
- Patients who are newly diagnosed with acute leukemia and hospitalized to receive
their initial 4 weeks of intensive induction chemotherapy for this disease
- Asthma or other reactive airway disease
- Sleep apnea
- Planned less than two week hospitalization
- Change in pain medications/sleeping medications/anxiety medications/antiemetics
during the trial
- Patients who have not completed their initial steroids
- Patients who are confused and unable to give informed consent
Lisa Blackburn, MS,RN,AOCNS
Ohio State University Comprehensive Cancer Center