New York, New York 10029


Purpose:

This study aims to calibrate the Multiple Sclerosis Functional Composite (MSFC) for home implementation in a phase 2 trial of lisinopril in multiple sclerosis. In this initial stage, participants are required to travel to the study site one day a week for three weeks to complete the MSFC. They are also required to complete the MSFC at home once weekly for three weeks using remote sensing technology and video conferencing.


Criteria:

Inclusion Criteria: 1. Males and females between the ages of 18 and 64. 2. Documented informed consent 3. Documented diagnosis of RRMS via 2010 McDonald Criteria 4. Normal blood pressure at baseline: 90-140 mmHg systolic AND 60-90 mmHg diastolic 5. Baseline score of 0-5.5 on Kurtzke's Expanded Disability Status Scale (EDSS) 6. Availability of a person in the home who is physically able and willing to steady the subject if s/he loses balance during the walk test. Exclusion Criteria: 1. Hypotensive at baseline: <90 mmHg systolic or <60 mmHg diastolic 2. Hypertensive at baseline: >140 mmHg systolic or >90 mmHg diastolic 3. Bradycardia at baseline: < 50 bpm


NCT ID:

NCT02369926


Primary Contact:

Study Director
Tomasz Sablinski, MD, PhD
Transparency Life Sciences

Ruthie Perez
Email: ruthie.perez@mssm.edu


Backup Contact:

Email: tarah.gustafson@mssm.edu
Tarah Gustafson


Location Contact:

New York, New York 10029
United States

Tarah Gustafson
Email: tarah.gustafson@mssm.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 23, 2017

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