1. To establish the culture positivity rate in adjustable suture strabismus surgery
2. To identify bacterial species and antibiotic susceptibility patterns of microorganisms
cultured from suture material
3. To compare suture contamination rates with techniques to reduce the suture contamination
Patients will be randomized into 1 of 2 groups: those who received 1 drop of 5%
povidone-iodine instilled directly over the sliding noose at surgery completion (group 1) and
those who did not receive povidone-iodine at the end of the surgery (group 2).
Institutional standard surgical preparation will be performed in all patients with 5%
povidone-iodine solution on the periocular skin and eyelid margins, followed by instillation
of 1 drop of 5% povidone-iodine into the conjunctival cul-de-sac.
All operations will be performed using a sliding noose technique with a polyglactin 6-0
suture (Vicryl, Ethicon Inc). If a patient undergoes surgery on more than 1 muscle in the
same eye, a 1-cm section of suture proximal to the knot will be collected from the
nonadjustable suture as a control. The control suture will be placed in a tube with 2 mL of
trypticase soy broth and agitated for 1 minute. At the end of surgery, patients in group 1
will receive a drop of povidone-iodine. A strip of neomycin sulfate, polymyxin B sulfate, and
dexamethasone ophthalmic ointment will be then applied into the lower conjunctival fornix to
patients in both groups.
- All strabismus patients age ≥ 18 years scheduled for strabismus surgery with
adjustable sutures at the Bascom Palmer Eye Institute will be invited to participate.
- Patient who has a history of allergy to povidone-iodine.
- Disorders affecting immune function.
- Patient who is unwilling to participate in the study