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Boston, Massachusetts 02215


The purpose of this feasibility study is to preliminarily evaluate the effects of Tai Chi - a mind-body exercise - on motor and cognitive function as well as quality of life in individuals recently diagnosed with Parkinson's disease (PD).

Study summary:

Specific Aim 1: To assess the feasibility of recruiting and retaining individuals with PD into a 6-month randomized controlled trial of Tai Chi exercise. Specific Aim 2: To collect preliminary data on the efficacy of Tai Chi on improving gait and balance dynamics, physical and cognitive function, exercise activity, self-efficacy, mood, and quality of life in individuals with PD.


Inclusion Criteria: - Individuals recently diagnosed with idiopathic PD (≤ 10 years) - Limited disease progression - If taking PD-related medication, willingness to undergo baseline and follow-up testing while off medication - Willingness to commit to the study protocols and complete Tai Chi program - Willingness to be videotaped and audio-recorded during testing Exclusion Criteria: - Diagnosis of any form of atypical parkinsonism - History of: stroke, head trauma, brain tumor, brain injury, seizures or other central nervous system condition, orthopedic impairment or other disease that could likely contribute to a gait disturbance or parkinsonism - Any severe, chronic condition or acute medical event for which participation in exercise programs is contraindicated (e.g. debilitating Rheumatoid Arthritis, history of frequent falls, unhealed fracture)** ** Unless the participant is able to obtain formal written approval from his/her treating physician granting permission to participate in our Tai Chi exercise program - Participation in brain stimulation within the past 3 months - Family history of seizures or unexplained loss of consciousness - Current history of dementia or severe psychiatric illness. Patients with mild (non-suicidal) depression and/or anxiety may be included - Acute illness requiring hospitalization within past 3 months - History of deep brain stimulation or other brain surgery - Participation in brain stimulation within the past 3 months - Regular use of walking aid - Significant Tai Chi experience (> 6 months training in past 2 years)



Primary Contact:

Principal Investigator
Peter M Wayne, PhD
Harvard University Faculty of Medicine

Backup Contact:


Location Contact:

Boston, Massachusetts 02215
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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