Expired Study
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Palo Alto, California 94304


Purpose:

Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are given.Pathophysiological respiratory depression -failure to respond to hypercapnia or hypoxia - is challenging to measure clinically.American Society of Anesthesiologist guidelines recommend suitable respiratory monitoring for 24 hours post cesarean delivery (CD). Use of capnograph will enable us to assess breath-by-breathe respiration in a population receiving neuraxial opioids - potentially at risk for respiratory depression. Our aim is to assess our ability to capture maternal postpartum respiratory parameters in a cohort following opioid neuraxial administration for CD.


Study summary:

The investigators wish to test the efficacy of capnograph in detection of apnea and respiratory depression in women following cesarean delivery. Currently, routine intensive monitoring such as the investigators propose is not performed, and many apneas may go undetected.


Criteria:

Inclusion Criteria: - American Society of Anesthesiologists physical status class I or II - Age between 18 and 45 - Gestational age greater than 37 completed weeks - Singleton pregnancy. Exclusion Criteria: - Contraindication for neuraxial analgesia (bleeding diathesis, neuropathy, severe scoliosis, previous spine surgery, local anesthetic allergy) - Allergies to postoperative medication (opioids, NSAIDs, acetaminophen) - Chronic opioid use - Opioid administration in the previous 12 hours - Inability to adequately understand the consent form - Blocked nose or nasal deformity.


NCT ID:

NCT02417038


Primary Contact:

Principal Investigator
Brendan Carvalho, MD
Stanford University


Backup Contact:

N/A


Location Contact:

Palo Alto, California 94304
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 22, 2017

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