Fluorescein is a dye agent that can be injected through an intravenous line. It has been
shown to help tell the difference between brain tumor tissue and normal brain tissue when it
is used together with a specialized filter on a microscope in the operating room. The
investigators plan to study the use of fluorescein in the removal of brain tumors at a low
1. Age of 18 or greater
2. Plan for elective removal of a brain tumor at UPMC Shadyside with either Dr. Engh or
1. History of adverse reaction to fluorescein.
2. Emergent surgical procedure (consent not feasible).
3. Creatinine of > 2.0 (drug is excreted renally).
4. Known ongoing pregnancy.