Expired Study
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Nashville, Tennessee 37232


This pilot clinical trial studies fluorine (F)-18 16 alpha-fluoroestradiol (18F-FES) positron emission tomography (PET)/computed tomography (CT) in imaging patients with desmoid tumors. 18F-FES binds to estrogen receptors, which are present on desmoid tumors, and gives off radiation that may be detected by PET and CT scans. The PET/CT scan forms an image that may show where tumor cells with estrogen receptors can be found in the body.

Study summary:

PRIMARY OBJECTIVES: I. Establish the avidity of desmoid tumors on 18F-FES PET/CT imaging. II. Correlate 18F-FES PET avidity with degree of estrogen receptor (ER) expression by immunohistochemistry (IHC). OUTLINE: Patients undergo 18F-FES PET/CT imaging over 30 minutes. After completion of study, patients are followed up for 30 days.


Inclusion Criteria: - Patients with biopsy-proven extra-abdominal desmoid tumors - Not currently on estrogen medication for birth control, menopause, or other reason - No anti-estrogen therapy for desmoid tumor within the past 6 months - Both sporadic desmoid tumors and those associated with familial adenomatous polyposis (FAP) syndromes will be included Exclusion Criteria: - Pregnancy or nursing patients - Patients who do not wish to participate



Primary Contact:

Principal Investigator
Katherine Hartley, MD
Vanderbilt-Ingram Cancer Center

Backup Contact:


Location Contact:

Nashville, Tennessee 37232
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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