Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line
to toes will decrease surgical site infections (SSI) by 30% when compared to patients who
receive routine standard of care (use of chlorhexidine cloths night before surgery and
morning of surgery).
Patients undergoing colorectal surgery will be randomized in a 1:1 fashion into two groups.
One will be standard of care using 2% Chlorhexadine Gluconate wipes night before surgery and
morning if surgery. The second group will be randomized into the study arm using 2%
Chlorhexadine Gluconate clothes from jaw line to toes night before surgery, morning of
surgery and daily post operative. Skin cultures will be obtained at time of consent, prior to
surgical procedure before surgical scrub and draping, post operative day 4 and at 30 day
follow up visit. Incision lines will be assessed daily by study staff for signs of surgical
site infection utilizing the CDC's 3 definitions of surgical site infections, superficial
incisional SSI, deep incisional SSI, and organ space SSI.
- 1. Patients > 18 years old scheduled for a colorectal surgical procedure ASA>2 OR
- Unable to consent
- Known allergy to any of the ingredients contained in SAGE chlorhexidine gluconate
- Current infection or history of abdominal infections.
- Patients on chronic steroids or immunosuppressive medications.