Expired Study
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New York, New York 10065


Purpose:

The purpose of this study is to look at air quality in cabs and see if the air quality inside taxi cabs is connected to increased risks for lung and heart health problems. Another purpose of the study is to see if putting an air filter inside the car may help improve the air quality and lower health risks. This is important because air pollution can be harmful to health. Air pollution is made up of very tiny particles (things) floating in the air around us, called particulate matter. Particulate matter is made up of dust, smoke, dirt, and gas fumes and can get into our bodies as we breathe. It has been linked to risk for lung cancer and heart disease. It is important because taxi drivers spend many hours of their day inside their cars. The investigators hope that this study will help them find out if using air filters inside cabs will help lower the levels of pollution in cabs and reduce its effects on the health of taxi drivers. They will use these results to educate the taxi driver community.


Study summary:

DRIIVE (Data and Research on Interventions to Improve the Vehicular Environment) is a community-engaged translational pilot project that will utilize a three parallel arm design to obtain preliminary data on associations between Particulate Matter (PM)/air pollution and physiologic measurements and biomarkers in taxi drivers, and to determine the impact of a HEPA filter (to remove PM and volatile organic compounds) intervention on such physiologic measurements and biomarkers. DRIIVE is funded by the New York State Department of Health Empire Clinical Research Investigator Program (ECRIP), which trains physicians in clinical research in New York. Drivers will be randomized to one of two groups: Intervention or Wait-list Control. The third group will be a Matched Nominated Peer Comparison Group, non-drivers who will participate in the same PM and physiologic and biomarker measurements and will serve as a control for non-driving related PM exposure and physiologic response. In total, three groups of 14 participants will be recruited: 1) Wait List Control group, who will receive a HEPA filter at the end of the 1 month participation period, 2) Intervention group, who will receive a HEPA filter two weeks into their participation period, and 3) PM reference group of peer non-drivers, who will also receive a HEPA filter at the end of the 1 month period of participation. The project will be completed within a 2 year timeframe.


Criteria:

Inclusion Criteria: Drivers: - Full-time New York City cab drivers; - Non Smokers (assessed by modified BRFSS smoking question within screening tool) ; - Male; - Between the ages of 21 and 90; - No immediate plans (within the next 3 months) to leave the City for vacation or for trips back to their home country, and no recent (within 3 months) travel; - Driver for at least 3 years; - Driving schedule does not include overnight shifts, nor does driver have an additional job overnight; - Able to identify 2-4 matched peers - Own a smart phone (in order to collect heart rate variability data) - Should self-report at least "Very well" level of English fluency (according to the standard US census question) - Have working cigarette lighter receptacle/socket inside taxi cab Non-drivers (Matched Peer Comparison Group) Excluding the driving requirements, non-drivers will be required to meet the same inclusion criteria: - Non Smokers (assessed by modified BRFSS smoking question within screening tool); - Live in the same New York City borough - Be of the same country or region of origin; - Similar length of stay within the U.S. (within 10 years); - Be within 10 years of the age of the driver who nominated them; - May work (full-time or part-time) in the following occupations: barber shops, shops/retail/sales, office work (administrative assistant), electrician, engineer, professor/teacher/other school-based occupation, accountant, health care worker, travel/tourism/hospitality, all of which must be non-smoking environments - Must have worked in any of these occupations for at least 1 year, and their current work schedule cannot include overnight shifts.* - Own a smart phone - Should self-report "Very well" or "Well level of English fluency (according to the standard US census question) *The requirement to have worked at least 3 years in the U.S. should minimize any acute health effects/disease due to high levels of contaminants associated with country of origin, for both drivers and Peers. Exclusion Criteria: Drivers: - Smoker or uses smokeless tobacco products; - Resides in a smoking household (where 1 or more household members smoke); - Has a sleep disorder (including insomnia, delayed sleep phase syndrome (DSPS), narcolepsy, night terror, sleep apnea, sleep walking); - Has a current or previous diagnosis of any type of cancer; - Has a diagnosis of an inflammatory, autoimmune, or chronic infectious disease (including rheumatoid arthritis, lupus, chronic liver disease, multiple sclerosis, fibromyalgia, inflammatory bowel disease, psoriasis, HIV); - Has a serious cardiopulmonary medical condition (including cardiovascular disease, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), restrictive lung disease, interstitial lung disease, asthma, acute or chronic bronchitis, cystic fibrosis, pneumonia, tuberculosis, pneumoconiosis, pulmonary hypertension, pulmonary embolism, pleural effusion, pneumothorax, obesity hypoventilation syndrome, neuromuscular lung disease). - Self reports "well" level of English fluency and indicate a preference for an interpreter. Non-drivers (Matched Peer Comparison Group) - Is a professional driver, mechanic, restaurant worker, factory/warehouse worker, or construction worker. - Smoker or uses smokeless tobacco products(assessed by BRFSS smoking classification questionnaire within screening tool); - Resides in a smoking household (where 1 or more household members smoke); - Has a sleep disorder (including insomnia, delayed sleep phase syndrome (DSPS), narcolepsy, night terror, sleep apnea, sleep walking); - Has a current or previous diagnosis of any type of cancer; - Has a diagnosis of an inflammatory, autoimmune, or chronic infectious disease (including rheumatoid arthritis, lupus, chronic liver disease, multiple sclerosis, fibromyalgia, inflammatory bowel disease, psoriasis, HIV); - Has a serious cardiopulmonary medical condition (including cardiovascular disease, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), restrictive lung disease, interstitial lung disease, asthma, acute or chronic bronchitis, cystic fibrosis, pneumonia, tuberculosis, pneumoconiosis, pulmonary hypertension, pulmonary embolism, pleural effusion, pneumothorax, obesity hypoventilation syndrome, neuromuscular lung disease). - Self reports "well" level of English fluency and indicate a preference for an interpreter.


NCT ID:

NCT02381626


Primary Contact:

Principal Investigator
Jennifer Leng, MD, MPH
Memorial Sloan Kettering Cancer Center


Backup Contact:

N/A


Location Contact:

New York, New York 10065
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 19, 2017

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