Expired Study
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Durham, North Carolina 27710


This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric environment for exercise performance at altitude. Subjects will complete a short, high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after this training phase, all subjects will be tested for maximum aerobic capacity at a simulated high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of mitochondrial oxidative capacity in a skeletal muscle biopsy. A group of individuals of similar characteristics completing this training program in a normoxic-normobaric environment will serve as a control.


Inclusion Criteria: - healthy, recreationally active or sedentary individuals Exclusion Criteria: - VO2max < 35 ml/kg/min - male 30 ml/kg/min - female - chronic cardiovascular or pulmonary diseases - history of pneumothorax - active smoker - pregnant women - non-english speaking - not in full mental capacity - blind - sickle cell trait or disease



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Durham, North Carolina 27710
United States

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Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 21, 2017

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