Expired Study
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Cincinnati, Ohio 45229


Purpose:

This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years.


Study summary:

This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years. We will follow these patients at 6 months and 1 year with Hyperpolarized Helium-3 Magnetic Resonance Imaging and image guided bronchial biopsies to detect early BOS and to better understand BO disease progression. The biopsies will provide future research for rapid determination of cellular and molecular mechanisms that lead to BOS and to facilitate identification and validation of translatable pharmaceutical targets.


Criteria:

Inclusion Criteria: - Lung Transplantation within the last 10 years or being assessed for possible lung transplantation. - Male or female - 0 to 25 years of age. Exclusion Criteria: - Standard MRI exclusion criteria as set forth by the CCHMC Division of Radiology - Inability to perform 10 second breath hold for 3He MRI scan - Bleeding disorders


NCT ID:

NCT02316392


Primary Contact:

Principal Investigator
Jason Woods, PhD.
Cincinnati Children's


Backup Contact:

N/A


Location Contact:

Cincinnati, Ohio 45229
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 21, 2017

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