Granuloma annulare is a benign, usually self-limiting, cutaneous dermatosis, which typically
presents as asymptomatic, flesh-colored or red papules, frequently arranged in an annular
pattern on the distal extremities. Although localized granuloma annulare is most commonly
observed, a generalized or disseminated form can occur. The etiology of granuloma annulare
is unknown, however, multiple inciting factors have been proposed. The purpose of the
investigators is to review the outcomes of treatment of granuloma annulare (GA) resistant to
standard regimens that resolved after a 3-months treatment course of monthly rifampin,
ofloxacin, and minocycline (ROM) therapy, successfully used to treat paucibacillary leprosy,
a disease with clinical and histopathologic similarity to GA.
We will document the regimen treatment each patient has had and then review the following
from the patient's chart to target our specific aims as outlined above.
1. What previous treatment options have been or/are currently being used?
2. How long did the patient take the treatment for?
3. Was the patient able to discontinue or become less dependent on prior treatment?
4. Was the disease process slowed by the treatment?;
5. Were there any side effects that the patient experienced with treatment?
- Patients with granuloma annulare who are resistent to the standard treatment.
- Response to the standard treatment of granuloma annulare.