The purpose of this study is to evaluate Vitamin D levels in thyroid cancer patients with
active disease compared with thyroid cancer patients in remission and patients with thyroid
Thyroid cancer is the most common endocrine related malignancy, increasing in incidence in
recent years. There are relatively few, well known factors, both genetic and environmental,
which predispose to the development of thyroid cancer. Vitamin D deficiency has been
associated with other cancers, but the association between vitamin D and thyroid cancer is
unknown. We plan to do a case control, pilot study to evaluate the relationship between
vitamin D levels and thyroid nodules, thyroid cancer in remission, and active thyroid
- Cases: History of Papillary, Follicular, Follicular Variant of Papillary, or Hurthle
cell thyroid cancer (both active disease and in remission).
- Controls: Individuals with a thyroid nodule, matched to cases for age, BMI, season of
vitamin D measurement.
- Participating in University of Nebraska Medical Center Thyroid Tumor and Cancer
Collaborative Registry database.
- Pregnant or breast feeding women
- Medullary thyroid cancer
- Anaplastic thyroid cancer
Nathan W Laney, MD
University of Nebraska Medical Center, Department of Internal Medicine, Section of DEM