Expired Study
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Baltimore, Maryland 21205


Purpose:

This research is being done to find out the best way to give narcotics for pain relief in adults with sickle cell disease and painful crisis. This study is a comparison of two ways of giving narcotics. The first way is what occurs now in the Emergency Acute Care Unit (EACU) where patients are given a single intravenous (iv) dose of a narcotic which is repeated by the nurse as needed to control the pain. The second way is to provide a single iv dose of narcotic and then allow the patient to push a button and receive one or more additional doses of narcotic when he/she thinks it is needed. Our hypothesis is that PCA will be a more effective way of controlling pain.


Criteria:

Inclusion Criteria: - Documented sickle cell disease - Signed consent in outpatient clinic or during a prior hospitalization - 18+ years of age - Seen in the ED with sickle cell pain crisis - this will be based on patients chief complaint that they are in a VOC. - Requires IV administration of narcotics (has failed oral narcotic therapy at home) - Must be 2 weeks since their last randomization on this study. Exclusion Criteria: - Contraindication to the use of IV narcotics - Hypotension with systolic blood pressure (SBP) ≤ 90 - Respiratory rate ≤9 - Altered mental status - Patient unable to understand how to use the PCA device - Patient unwilling to use PCA device - Pulse oximeter reading of ≤ 94% on room air - Patient is allergic to IV morphine & hydromorphone & fentanyl. - Patient is allergic to oral hydromorphone & morphine & oxycodone - Patient has been randomized on this study 3 times before


NCT ID:

NCT00711698


Primary Contact:

Principal Investigator
Sophie Lanzkron, MD
Johns Hopkins University


Backup Contact:

N/A


Location Contact:

Baltimore, Maryland 21205
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

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