Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Englewood, Colorado 80113


Purpose:

Atomoxetine is the only medication that is currently approved by the FDA for the treatment of attention deficit hyperactivity disorder in adults. It has gained recent interest as an alternative medication for treating attentional problems related to traumatic brain injury (TBI), but it's effectiveness in this population has not been studied. There are a number of advantages of Atomoxetine over traditional neuro-stimulant medications currently used for attentional disorders after traumatic brain injury. This study will use a randomized double-blind placebo-controlled crossover design to investigate the efficacy of atomoxetine to improve attention, behavioral function, and depression in adults with TBI


Criteria:

Inclusion Criteria: - History of TBI - Moderate to severe TBI as indicated by GCS score of 12 or less; or PTA of seven days or more - at least one year post injury - between the ages of 18-65 (inclusive) - symptoms consistent with attentional dysfunction - consent to participate in study Exclusion Criteria: - history of any conditions that would prohibit standard neuropsychological testing - non-English speaking (to the extent that would limit ability to complete study measures) - prior history of significant psychiatric illness requiring hospitalization - epilepsy - cardiovascular disease or risks including: dysrhythmias, angina, myocardial infarction, uncontrolled hypertension, valvular heart disease including mitral valve prolapse - use of any monoamine axidase inhibitor or any other drug affecting brain monoamine concentrations - severe renal or hepatic impairment - pregnant or lactating


NCT ID:

NCT00702364


Primary Contact:

Principal Investigator
David L Ripley, MD
Craig Hospital


Backup Contact:

N/A


Location Contact:

Englewood, Colorado 80113
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.