Expired Study
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Pittsburgh, Pennsylvania 15213


This study will compare Eustachian tube function (ETF) testing in adults with intact tympanic membranes (TM) using a pressure chamber to that obtained using standard methods requiring a non-intact TM.

Study summary:

The investigators propose to introduce new test methods and protocols to our laboratory for better clinical characterization of Eustachian tube function in ears with intact TM's. These test will be done in a pressure-chamber and will use previously published and newly developed methods. Participation will require a minimum of 5 visits to the ENT Research Center, 1 for myringotomy (putting a small hole in the eardrum) and 4 for ETF testing. Hearing testing will be done at entry and exit; otoscopy (looking at the ears) and tympanometry (a test done with an earplug and varying pressures in the ear canal) are done at every visit.


Inclusion Criteria: - >18 years old - Normal middle-ear status Exclusion Criteria: - Chronic illness including asthma, pulmonary, or cardiac problems - Pregnancy - >10 dB hearing loss in any of the speech frequencies - Past history of sensitivity or allergic reaction to lidocaine or related compounds



Primary Contact:

Principal Investigator
William J Doyle, PhD
University of Pittsburgh

Backup Contact:


Location Contact:

Pittsburgh, Pennsylvania 15213
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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