Expired Study
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Omaha, Nebraska 68131


Purpose:

If you are allergic to ragweed, and not taking certain medications, you will be asked to have blood drawn. We will perform experiments on your blood cells.


Study summary:

Adult ragweed allergic subjects will have blood drawn. Basophils will be enriched and stimulated with allergen and controls. Supernatants from these stimulations will be assayed for cytokines and histamine.


Criteria:

Inclusion Criteria: - Ages 19 to 50 - At least 2 year history of ragweed allergic rhinitis - Positive skin prick tests to ragweed >5 mm wheal diameter - IgE <700 iU/m Exclusion Criteria: - Use of prohibited medications (e.g. antihistamine in past 7 days and topical or oral corticosteroids in past 1 month, beta-agonist or theophylline for 2 days. - History of immunotherapy in the past 2 years - Exposure to Omalizumab in the past 2 years - Clinically significant non-allergic or perennial rhinitis to avoid mediator release due to environmental allergens - Asthma other than mild intermittent - Women of childbearing potential who are not on an accepted form of birth control, as well as women who are breastfeeding - Known sensitivity to study drug Xolair - Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study - Patients with a previous history of cancer - Use of any other investigational agent in the last 30 days


NCT ID:

NCT00673218


Primary Contact:

Principal Investigator
Robert G Townley, MD
Creighton University


Backup Contact:

N/A


Location Contact:

Omaha, Nebraska 68131
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 18, 2018

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