Primary Aim # 1: Determine the willingness of the public to participate in an intervention
trial - NutritionQuest's Alive!TM - available in a public forum.
Aim #1 Hypotheses: Less than 10% of individuals visiting the NutritionWeek site will
register to participate in the Alive!TM Intervention; 70% of these individuals will complete
the full intervention.
Primary Aim # 2: To determine among individuals enrolled in the Alive!TM intervention,
changes in measurements of body composition from pre- to post-intervention.
Aim #2 Hypotheses: Participation in Alive!TM will result in positive changes in body
composition, including reduction of body weight, percent body fat and blood LDL and an
increase in blood HDL cholesterol.
1. Educate the public on the relationship between diet, weight and chronic disease
2. Collect data for future research
3. For participants of the Oregon Museum of Science and Industry (OMSI) portion of this
study, we also provide a diet assessment and optional 3-month intervention
Researchers will have a display at OMSI coincidental with the Body Worlds 3 exhibit and at
local health fairs. Participants will be recruited from the attendees of the OMSI Body
Worlds 3 exhibit as well as general OMSI visitors from July through October 2007 and from
health fairs at later dates.
No identifiable information will be collected; only gender, year of birth, race and
ethnicity are collected on any participant.
Subjects under age 18 can participate in any or all of the following: a brief online,
touch-screen assessment of eating and physical activity (health screening for immediate,
printed feedback), physiologic measurements (height, weight, hip and waist circumference,
percent body fat, blood pressure).
Subjects who are age 18 and over can participate in any or all of the following: a brief
online, touch-screen assessment of eating and physical activity (health screening for
immediate, printed feedback), physiologic measurements (height, weight, hip and waist
circumference, percent body fat, blood pressure), finger prick to assess blood glucose and
lipid levels as well as DNA sample (mouthwash swish).
For participants of the OMSI portion of this study, adults may also choose to join a 3-month
online lifestyle intervention (Alive!™). Participants who enroll in the 3-month intervention
will receive 12 intervention messages over a 3-month period. Each of the messages will take
about 5 to 10 minutes to read. At the end of this 3-month period, participants will receive
a post-assessment health screening at the Oregon Health & Science University (OHSU) Clinical
and Translational Research Center. This post-assessment will include completion of a diet
and physical activity assessment, fasting blood measures of glucose and lipids, blood
pressure, weight and height.
All visitors to the display area and all research subjects will be offered educational
Instruments used, for OMSI participants only:
The Alive!TM lifestyle intervention is a web-based diet assessment program designed to help
individuals evaluate their diet and make healthy changes via tailored e-mail correspondence.
This program is operated by NutritionQuest out of Berkeley, California; utilizing the Block
questionnaires, designed and validated over many years by Dr. Gladys Block, and now in use
by researchers and health practitioners world-wide.
De-identified data will be stored for future analyses and will be used in descriptive
analyses to provide information on the distribution of body size variables and how they
relate to reported dietary intake. DNA data from cheek cell samples will be linked by
identification number to dietary intake and physiologic measures. Though de-identified, this
data may still be used to identify genetic profiles of individuals with various physiologic
For OMSI participants only:
Alive!TM lifestyle intervention data will be used to determine predictors of change in
physiologic and reported intake measures pre and post-intervention, using analysis of
variance. At the time of analyses ALL data (including Alive!TM participant data) will be
- Attendees of public health fairs
- General population
- Under the age of 18
- Above the age of 18