Expired Study
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Ann Arbor, Michigan 48103


Purpose:

This study is to determine if subjects with .systemic sclerosis have stimulatory autoantibodies to the PDGF receptor and to confirm activation (phosphorylation) of the PDGF receptor in skin sites with varying degrees of skin thickening


Study summary:

Pilot study to assess whether patients with systemic sclerosis have stimulatory autoantibodies to the PDGF receptor and to confirm activation (phosphorylation) of the PDGF receptor in skin sites with varying degrees of skin thickening


Criteria:

Inclusion Criteria: 1. Fulfill the American College of Rheumatology criteria for systemic sclerosis or: 2. Have no diseases that result in primary fibrosis of an organ system, including the skin and do not have an autoimmune disease Exclusion Criteria: 1. If the subject has systemic sclerosis resulting from an environmental exposure 2. If the subject has an autoimmune disease excluding scleroderma 3. If the subject has an active infection (including, but not limited to hepatitis B, hepatitis C and HIV) 4. If the subject has been treated with cyclophosphamide in the past 8 weeks. 5. If the subject is prone to bleeding because they are on medications that thin the blood or have a low platelet count.


NCT ID:

NCT00667134


Primary Contact:

Principal Investigator
Kristine Phillips, MD
University of Michigan


Backup Contact:

N/A


Location Contact:

Ann Arbor, Michigan 48103
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

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