The goal of this study is to determine if 8-week dietary treatment with the omega-3 fatty
acid docosahexaenoic acid (DHA) improves attention performance and associated cortical
activity and metabolism in 8 - 10 year old males that were not breast-fed during infancy.
1. Male subjects between the ages of 8 - 10 years.
2. Not breast-fed during infancy
3. Right hand dominant
4. Attending school at appropriate grade level
5. Normal body-mass index (BMI)
6. Ability and willingness to provide assent and informed, written consent from at least
one biological parent.
7. Present with biological parent
8. No current general medical or psychiatric illness.
9. Medication free.
10. Normal intelligence as assessed by the Kaufman Brief Intelligence Test.
11. Willingness to maintain current dietary habits.
1. Inability or unwillingness to provide consent.
2. Antecedent or concurrent serious medical illness.
3. A lifetime history of any significant axis I psychiatric disorder ( i.e. bipolar
4. Patients who have received any psychoactive medications, current and lifetime.
5. Clinically unstable medical disease, including cardiovascular, hepatic insufficiency,
severe renal impairment, gastrointestinal, pulmonary, metabolic, endocrine, obesity
or other systemic disease.
6. History of seizures, excluding febrile seizures in childhood.
7. Patients requiring treatment with any drug which might obscure the action of study
the study treatment.
8. Less than normal intelligence.
10. Cerebral aneurysm clip
11. Cochlear implant
12. Metal fragments lodged within the eye
14. Necessity of sedation (no sedation will be given).
15. History of loss of consciousness > 10 minutes in duration