1. To evaluate the absorption and elimination of varenicline Formulation A transdermal
delivery system [TDS (patch)] compared to varenicline immediate release tablet
2. To evaluate the adhesion of the varenicline Formulation A patch.
3. To evaluate the safety and tolerability of a single application of the varenicline
patch and a single oral dose of the varenicline immediate release tablet (CHANTIX®).
- healthy adult smokers
- Significant blood, kidney, lung, gastrointestinal, heart, liver, psychiatric, or
- Illegal drug usage