Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

St. Louis, Missouri 63110


Purpose:

To assess the feasibility of administering induction chemotherapy with gemcitabine and docetaxel followed by concurrent radiation and continuous infusion 5FU and consolidation gemcitabine/docetaxel chemotherapy.


Criteria:

Inclusion Criteria: - Patients must have biopsy-proven, resected with curative intent cholangiocarcinoma, gallbladder, pancreatic or ampullary adenocarcinoma. - Patients must be 18 years or older. - Patients must have a NCI CTC Performance Status of 0-2. - Patients must not have any prior chemotherapy or radiation therapy for this current malignancy. - At least 3 weeks should have elapsed since any surgery requiring general anesthesia. - Patients must have no prior malignancies except for basal or squamous skin cancers, cervical carcinoma-in-situ, unless in remission for >5years - Pregnant patients are not eligible. Non-pregnant status will be determined in all women of childbearing potential. All patients will be required to use an effective means of contraception if sexually active during therapy. - Initial Required Laboratory Values: - Absolute neutrophil count ≥ 1,500/mm3, platelet count ≥ 150, 000/mm3, and hemoglobin ≥ 9 g/dL. - Serum creatinine should be ≤ 2 mg/dL. - Serum bilirubin should be ≤ 3.0 mg/dL (biliary stents allowed). - Serum transaminases should be ≤ 5-fold the institutional upper limits. - Patients must not have any co-existing severe medical illnesses, such as unstable angina, uncontrolled diabetes mellitus, uncontrolled arrhythmia or uncontrolled infection. - Patients must be able to sign an informed consent. Exclusion Criteria: - None


NCT ID:

NCT00660699


Primary Contact:

Principal Investigator
Benjamin Tan, M.D.
Washington University School of Medicine


Backup Contact:

N/A


Location Contact:

St. Louis, Missouri 63110
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 18, 2018

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.