The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
Clinicians use lidocaine intravenously in a fashion that suggests that it might have
analgesic effects. Therefore, we test the hypothesis that lidocaine reduces pain intensity
in response to experimental pain.
- Healthy Adult Volunteers, age >19 years
- History of Substance Abuse
- Coronary Artery Disease (CAD): unstable
- Congestive Heart Failure (CHF): unstable
- Heart Arrhythmia: symptomatic
- Chronic Obstructive Pulmonary Disease (COPD)
- Lidocaine Allergy
- Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I
disorders include depression, anxiety disorders,bipolar disorder, ADHD, and
schizophrenia. Axis II: borderline personality disorder, schizotypal personality
disorder, antisocial personality disorder, and mild mental retardation.
- Presence of Contraindications for MRI
- Presence of electronically, magnetically, and mechanically activated implants
- Electronically, magnetically, and mechanically activated implants
- Ferromagnetic or electronically operated active devices like automatic cardioverter
- Cardiac pacemakers
- Metallic splinters in the eye
- Ferromagnetic haemostatic clips in the central nervous system (CNS)