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Nashville, Tennessee 37240


Purpose:

The purpose of this study is to compare the effectiveness of ondansetron, metoclopramide, and promethazine for the treatment of nausea in the adult emergency department population. We hypothesize that a single intravenous dose of ondansetron is more effective in reducing nausea than a single IV dose of metoclopramide, promethazine or normal saline placebo in undifferentiated adult emergency department patients.


Criteria:

Inclusion Criteria: - All patients age 18 or older who present to the ED with a complaint requiring antiemetic treatment who do not meet the exclusion criteria. Exclusion Criteria: - Patients less than 18 years of age - Unstable patients with SBP < 90 - Patients with a stated or documented allergy to any of the study medications - Patients whose nausea rating if < 40 on the pretreatment VAS scale - Patients who have received a commonly accepted antiemetic within the previous 24 hours - Patients unwilling or unable to complete the assessment tool before and 30 minutes after study drug dosing


NCT ID:

NCT00655642


Primary Contact:

Principal Investigator
Tyler W Barrett, MD
Vanderbilt University


Backup Contact:

N/A


Location Contact:

Nashville, Tennessee 37240
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2018

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