Expired Study
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Zanesville, Ohio


Purpose:

This study will compare the safety and efficacy of once daily dosing of aliskiren to twice daily dosing of aliskiren in patients with moderate hypertension


Criteria:

Inclusion Criteria: - Have diagnosis of uncomplicated essential hypertension; newly diagnosed or who have not received antihypertension medication within 4 weeks of visit 1 must have an office cuff mean sitting Diastolic Blood pressure (msDBP) > 100 mmHg and < 110 mmHg at visit 1. If patient is receiving antihypertensive treatment, must have a cuff msDBP > 95 mmHg and < 110 mmHg at visit 1 - Prior to randomization, all patients must have an office cuff msDBP >or= 100 mmHg and <or = 110 mmHg. Exclusion Criteria: - Participation in another aliskiren trial or previous treatment with aliskiren during last 6 months and who qualified to be randomized or enrolled into the active drug treatment period - Pregnant or nursing women - Women of child bearing potential unwilling to use protocol specific contraceptive methods - Office cuff blood pressure of msDBP ≥ 112 mmHg and/or mean sitting Systolic Blood Pressure (msSBP) ≥ 200 mmHg). - Secondary form of hypertension - History of heart failure New York Heart Association (NYHA Class II, III and IV) - Previous history of hypertensive encephalopathy or stroke, transient ischemic attack (TIA), heart attack, coronary bypass surgery or any percutaneous coronary intervention (PCI) - Elevated Serum potassium (> or = 5.3 mEq/L (mmol/L) at Visit 1 - Type 1 or Type 2 diabetes mellitus not well controlled - Other protocol-defined inclusion/exclusion criteria may apply


NCT ID:

NCT00654875


Primary Contact:

Principal Investigator
Novartis
Novartis


Backup Contact:

N/A


Location Contact:

Zanesville, Ohio
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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