The purpose of this study is to determine whether or not the injection site of cytokines, or
growth factors, has an effect on peripheral blood stem cell collection.
The purpose of this study is to determine the preferred injection site for G-CSF and GM-CSF,
which are cytokines, or growth factors. The doctor may also choose to use these growth
factors in combination with chemotherapy to increase the number of stem cells in the blood.
Both options are established and are effective in increasing the number of stem cells in the
Patients will receive one shot under the skin twice a day for approximately 12-15 days after
receiving chemotherapy through the time your cells are being collected. Patients will be
randomly assigned to receive growth factors administered either to their abdomen or to their
extremities. Both shots will always be given either in the abdomen or in the extremities.
- All patients undergoing autologous peripheral blood stem cell transplant (PBSC) for
relapsed/refractory Hodgkin's disease, non-Hodgkin's lymphoma, or patients with
myeloma. All patients must meet criteria for transplantation.
- Patients with active, invasive/systemic fungal infection.
- Patients who are pregnant or lactating females.
- Patients with active CNS malignant disease or life expectancy limited by diseases
other than the disease for which the patient is being transplanted.
- Also, patients cannot have known hypersensitivity to either G-CSF or GM-CSF.