Expired Study
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Memphis, Tennessee 38138


The primary purpose of this study is to determine whether LY2181308 in combination with docetaxel is safe and effective treatment for hormone refractory prostate cancer patients.


Inclusion Criteria: - Histologically or cytologically confirmed adenocarcinoma of the prostate which is metastatic and/or unresectable - Hormone refractory prostate cancer defined as progressive based by documented 2 increase PSA values over a previous reference value. - ECOG status 0-2 - Adequate hematological functions, liver and renal functions Exclusion Criteria: - Known hypersensitivity to docetaxel or taxane therapy - Documented central nervous system or leptomeningeal metastasis at time of study entry - Had prior treatment with chemotherapy, bone seeking radionucleides in past 6 weeks prior to enrollment, or radiotherapy involving more than 25% of marrow producing area. - Evidence of painful and/or destructive bone metastases for which radiation therapy, biophosphonates or boneseeking radionucleides are necessary. - Have received treatment in the last 30 day with a drug which has not received regulatory approval for any indication at the time of study entry.



Primary Contact:

Study Director
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon-Fri 9AM-5PM Eastern time (UTC/GMT-5 hours, EST)
Eli Lilly and Company

Backup Contact:


Location Contact:

Memphis, Tennessee 38138
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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