The purpose of this study is to evaluate the efficacy of tattoo removal using topical
imiquimod, 5% cream in conjunction with the 1064nm Nd:YAG laser. This procedure for tattoo
removal will be compared to a laser removal alone.
Inclusion criteria includes: patients of both genders with Fitzpatrick skin types I-IV who
are 18-65 years of age and who has 2 tattoos from 2 to 10 cm in diameter, of similar age
which contains black and/or blue ink in areas that can be covered. Exclusion criteria
includes: tattoos in chronically sun exposed areas, larger than 25 cm2,pregnancy,breast
feeding state, immunosuppressed patients, history of autoimmune or connective tissue
disorders, hypersensitivity to imiquimod, active sunburn, current tan, use of coumadin,
aspirin , vitamin E or non-steroidal anti-inflammatory agents for the past 10 days.
- 2 tattoos no larger than 25cm2, professionally made, with approximately the same age,
containing blue/black ink.
- Hypersensitivity to imiquimod
- Current sun tan
- Use of vitamin E, non-steroid anti-inflammatory drugs, coumadin or aspirin for the
past 10 days
- Amateur tattoos
- Breast-feeding status
- Auto-immune diseases.