Pittsburgh, Pennsylvania 15232


After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.


Inclusion Criteria: - Identified gene mutation - Personal history of colorectal cancer diagnosed ≤ 50 - Personal history of cancer with tumor studies suggestive of Lynch syndrome - Personal history of multiple primary tumors associated with a hereditary cancer syndrome (colorectal, uterus, stomach, ovary, small bowel, hepatobiliary tract, transitional cell carcinoma of the renal pelvis/ureter, brain) - Personal history of one of the above cancers and a family history of one or more of the above cancers - Personal or family history of diffuse gastric cancer - From a known genetic predisposition family - Personal history of > 10 colon adenomas (cumulative over a lifetime) - Personal history of any number of hamartomatous polyps - Personal history of multiple large (> 1cm) serrated polyps to right of sigmoid Exclusion critera: - Individuals under the age of 8 - Individuals who cannot travel to Pittsburgh for in-person enrollment - Individuals who cannot provide informed consent



Primary Contact:

Principal Investigator
Randall E Brand, MD
University of Pittsburgh

Randall E Brand, MD
Phone: 412-623-3105
Email: brandre@upmc.edu

Backup Contact:

Email: dudleyre@upmc.edu
Beth Dudley, MS, MPH, CGC
Phone: 412-623-3105

Location Contact:

Pittsburgh, Pennsylvania 15232
United States

Randall E. Brand, MD
Phone: 412-623-3105
Email: brandre@upmc.edu

Site Status: Recruiting

Data Source: ClinicalTrials.gov

Date Processed: January 17, 2018

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