Continuous albuterol has become the standard of care for patients in status asthmaticus. We
have previously performed an in-vitro study comparing 4 different brands of continuous
nebulizers. We now want to compare the in-vitro with the in-vivo performance of the brand we
use. we hypothesize that there will be no difference between in-vivo and in-vitro results.
There will be no intervention to the patients. Nebulizers will be used as per current
policies and procedures. They will only be marked on the outside at the water level every 2
hours for the first 6 hours. Once ready to be discarded will be collected for laboratory
testing Once in the laboratory, nebulizers will be weight on a precision scale without
liquid, then they will be filled with normal saline to the first mark (6th hour) and
re-weight. The nebulizers will be filled to next mark and re-weight until 200 mls. of total
volume are achieved. Solution output will be calculated as the weight difference between the
2 hour periods.
- Pediatric patients admitted to Pediatric Intensive Care Unit due to status
asthmaticus, requiring continuous albuterol nebulization.
- Patients requiring invasive or non-invasive ventilation.