Chicago, Illinois 60614


Purpose:

The hypothesis of this study is that children with severe primary immunodeficiencies will benefit from early stem cell transplantation utilizing a reduced intensity conditioning regimen. This regimen is associated with a low risk of complications and will lead to correction of the underlying immunological defects.


Criteria:

Inclusion Criteria: - Must show one of the following diseases: - SCIDS - Hyper-IgM - Wiskott-Aldrich Syndrome - Chediak-Higashi and Griscelli Syndromes - X-Linked Lymphoproliferative Diseases - IPEX Syndrome - NEMO Syndrome - other severe immunodeficiency diseases not stated above at the discretion of the Principal Investigator - Informed Consent - Adequate Renal Function - Adequate Liver Function - Adequate Cardiac Function - Adequate Pulmonary Function - Adequate Performance Statue - Adequate Venous Access Exclusion Criteria: - Patient/Family has not signed informed consent - Patient does not have a clear diagnosis of a severe immunodeficiency disease - A suitable donor for the patient cannot be found - Patient is HIV positive - Patient has active Hepatitis B - Patient is pregnant - Patient is considered unsuitable for transplant at the discretion of the Principal Investigators or the medical director


NCT ID:

NCT00613561


Primary Contact:

Principal Investigator
Morris Kletzel, MD
Children's Memorial Hospital

Morris Kletzel, MD
Phone: 773-880-4562
Email: mkletzel@childrensmemorial.org


Backup Contact:

Email: cschaefer@childrensmemorial.org
Colleen E Schaefer, BS
Phone: 773-880-3459


Location Contact:

Chicago, Illinois 60614
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 23, 2018

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