Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures
and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the
face. SWS is also accompanied by an increased pressure within the eye (glaucoma) which can
develop very early in life.
Glaucoma represents a group of ocular disorders that are characterized by the loss of
retinal ganglion cells and their axons, damage to the optic nerve, and gradual loss of
visual field. Recently, several studies provided evidence that there is a potential role of
the immune system in the pathogenesis of glaucoma.
These findings suggest that there might be changes in systemic humoral immunity possibly
underlying the optic neuropathy in at least some glaucoma patients.
The ocular antibody profile in patients with SWS is unknown.The researchers want to study on
blood and tear drop samples from patients with SWS to determine the incidence of ocular
antibodies in patients with this syndrome.
- Male and female volunteers with SWS of all ages
- Volunteers without SWS