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Irvine, California 92612


Purpose:

Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face. SWS is also accompanied by an increased pressure within the eye (glaucoma) which can develop very early in life. Glaucoma represents a group of ocular disorders that are characterized by the loss of retinal ganglion cells and their axons, damage to the optic nerve, and gradual loss of visual field. Recently, several studies provided evidence that there is a potential role of the immune system in the pathogenesis of glaucoma. These findings suggest that there might be changes in systemic humoral immunity possibly underlying the optic neuropathy in at least some glaucoma patients.


Study summary:

The ocular antibody profile in patients with SWS is unknown.The researchers want to study on blood and tear drop samples from patients with SWS to determine the incidence of ocular antibodies in patients with this syndrome.


Criteria:

Inclusion Criteria: - Male and female volunteers with SWS of all ages Exclusion Criteria: - Volunteers without SWS


NCT ID:

NCT00610402


Primary Contact:

Principal Investigator
John S Nelson, M.D,PhD
Beckman Laser Institute University of California Irvine


Backup Contact:

N/A


Location Contact:

Irvine, California 92612
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 19, 2018

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