Expired Study
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Charleston, South Carolina 29464


Purpose:

Purpose: The purpose of this study is to provide tight blood sugar control using insulin given through the veins at the time of kidney transplantation and up to 3 days after surgery. After release from the hospital, the patient will control blood sugar with subcutaneous insulin injections or pills. With this approach, outcomes should improve for diabetic transplant patients such as longer life of the new kidney, fewer hospital readmissions, decreased associated infections, and other advantages. Hypothesis: It is hypothesized that intensive glycemic control will lead to better clinical and biochemical outcomes and improved long-term graft survival.


Study summary:

Research Design: A randomized control trial comparing intensive intravenous insulin (IVI) for use in the hospital followed by intensive subcutaneous (sc) insulin use for in-patient and out-patient glycemic control will be conducted.


Criteria:

Inclusion Criteria: - 18 years of age and greater, - Diabetes diagnosis (Type 1 and Type 2, awaiting a living or cadaveric renal transplant, renal transplant candidates admitted to MUSC medical center for a donor kidney, FBG >100 mg/dL per admission screening labs, random BG >120mg/dL per admission screening labs, and - Willing and able to provide informed consent Exclusion Criteria: - History of an active GI bleed in the previous 3 mos, - Scheduled to receive a simultaneous pancreas transplant, - History of a functioning pancreatic transplant, - Patient currently managed on an insulin pump, - Unable or unwilling to provide informed consent, and - Unable to commit to the study protocol including the outpatient follow-up phase of care


NCT ID:

NCT00609986


Primary Contact:

Principal Investigator
Kathie L. Hermayer, MD, MS
Medical University of South Carolina, Division of Endocrinology


Backup Contact:

N/A


Location Contact:

Charleston, South Carolina 29464
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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