Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Tyler, Texas 75708


Purpose:

To determine the safety and efficacy of azithromycin, rifabutin and ethambutol given three times weekly in the treatment of lung infection with M. avium complex


Criteria:

Inclusion Criteria: - Meet American Thoracic Society criteria for nontuberculous lung disease: two or more AFB smear positive, culture positive sputums or bronchoscopic samples and/or two or more AFB smear negative respiratory samples with moderate to heavy growth (2+-4+); abnormal CXR consistent with M. avium lung disease; abnormal CXR consistent with M. avium lung disease; absence of other lung pathogens (except for the coexistence of M. abscessus). - Age 18 and older - Pretreatment isolate of M. avium complex available for MIC determination - Baseline laboratory and clinical testing for baseline CBC, Chemistry (including liver enzymes), hearing test, visual acuity and color discrimination - Available for long term followup Exclusion Criteria: - History of macrolide or rifamycins allergy - Laboratory evidence of mycobacterial resistance to azithromycin - Children less than 18 years of age - If a menstruating female, not pregnant and on adequate birth control - HIV+ or at risk


NCT ID:

NCT00598962


Primary Contact:

Principal Investigator
Richard J Wallace Jr., M.D.
The University of Texas Health Science Center at Tyler


Backup Contact:

N/A


Location Contact:

Tyler, Texas 75708
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.