Expired Study
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Philadelphia, Pennsylvania 19104


Purpose:

A correlation between obesity and male fertility has been observed in a few clinical studies. Normal weight men appear to have higher sperm concentrations and sperm motility when compared to obese men, suggesting that weight loss might improve sperm function. However, there also are reported cases of severe male factor infertility following weight loss surgery in previously fertile men. The aim of this study is to determine if there are differences in the semen analyses and hormone levels of men obtained before and after undergoing weight loss (bariatric) surgery. This will direct future research and treatment.


Study summary:

We will recruit 60 subjects for this study. Volunteers will provide pre-operative semen and blood samples prior to undergoing weight-reduction surgery. Those with normal pre-operative sperm samples will be invited to continue participating in the study by providing subsequent post-operative semen samples and hormonal testing over a two year time period. It is estimated to take approximately one year to enroll the desired 60 subjects. The study will conclude two years from the last enrollment. The main analysis will be a comparison of sperm concentrations over time.


Criteria:

Inclusion Criteria: - Adult male subjects between the ages of 18-65 undergoing bariatric surgery Exclusion Criteria: - Subjects with abnormal sperm analysis


NCT ID:

NCT00596739


Primary Contact:

Principal Investigator
Samantha F Butts, MD, MSCE
University of Pennsylvania


Backup Contact:

N/A


Location Contact:

Philadelphia, Pennsylvania 19104
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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