Bone metabolism is adversely affected by severe burns in children for a period of time.
More closely monitored biochemical and radiologic parameters of bone and mineral metabolism
will increase the likelihood of earlier detection of abnormalities and possible therapeutic
- Children age 5-18 years old with at least 40% or more of their body burned.
- Anyone with a burn covering less than 40% of the body or whose burn covers the front
of both hipbones.
- Anyone younger than 5 years old, anyone with a history of cancer or other metabolic
disease process, or anyone who is pregnant or has an allergy to Tetracycline will
also be excluded.
- Anyone who has participated in an investigational drug trial within the past 60 days
from date of admission will be excluded from this study.