Expired Study
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Houston, Texas 77030


Purpose:

To find out if a single dose of Parcopa®, a form of levodopa that dissolves in your mouth, works faster than regular oral levodopa which is swallowed, in fluctuating PD patients.


Criteria:

Inclusion Criteria: - Male or female between the age of 31 and 80 -Diagnosis of idiopathic Parkinson's disease for at least three years duration - Patients requiring levodopa for their PD - Good subjective response to levodopa - Fluctuating symptoms defined by wearing off phenomenon, any dyskinesia, and/or dose failures - A UPDRS -off- motor score of at least 25 - Subjects willing to give informed consent - Subjects who are able and willing to comply with study procedures - If female of child-bearing potential, will use one of the approved birth control measures: 1. Hormonal contraceptives 2. Spermicidal and barrier 3. Intrauterine device 4. Partner sterility Exclusion Criteria: - Subjects with evidence of significant dementia - Subjects with significant oral lesions - History of unstable cardiac disease including angina or congestive heart failure within 3 months prior to study entry - History of clinically significant renal disease including renal insufficiency of sufficient degree to require adjunctive treatment or dietary restrictions - History of clinically significant hepatic disease, including previously documented cirrhosis or hepatic insufficiency or jaundice within 3 months prior to study entry. - Subjects with poor response to levodopa - Women who are pregnant, breast-feeding, or planning to become pregnant during this study are excluded from participation due to unknown effects of the study drug on the fetus.


NCT ID:

NCT00590122


Primary Contact:

Principal Investigator
William G Ondo, MD
Baylor College of Medicine


Backup Contact:

N/A


Location Contact:

Houston, Texas 77030
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

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