The purpose of this project is to further characterize inherited predisposition to breast
cancer mediated by specific BRCA alleles (BRACA1 185delAG and 5382insC; BRCA2 6174delT) among
- Patients are eligible for the study if they are over 18 years of age, identify their
ancestry as Jewish (both Sephardic and Ashkenazi Jews are eligible), have or have had
a diagnosis of breast cancer, and are able to give informed consent.
- Relatives, age 18 or older, of the patients who meet eligibility criteria above and
are found to have a specific BRCA1 or BRCA2 mutation if they are able to give informed