Expired Study
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Rochester, Minnesota 55905


Purpose:

To test if secretin-enhanced CT is a useful noninvasive screening tool for pancreatic cancer in a high-risk population.


Study summary:

By distending the pancreatic duct with secretin injection, we believe ductal dilation and cutoff will be accentuated. The investigators will be able to take advantage of this physiologic effect of secretin, by obtaining multi-planar scans with isotropic resolution using a 64-channel CT system.


Criteria:

Inclusion Criteria: - Persons 50 years or older with recently diagnosed diabetes (within 2 years), with at least one of the following: no family history of diabetes, abdominal discomfort, anorexia, weight loss, elevated serum CA 19-9, or those undergoing EUS with or without Fine Needle Aspiration (FNA) for pancreatic cancer screening ; OR - Persons 35 years old or older with familial pancreatic cancer with 2 or more first degree relatives with pancreatic cancer; OR - Persons 35 years old or older with Peutz-Jeghers syndrome; OR - Persons 35 years old or older with suspicious clinical symptoms of pancreatic cancer, but had normal CT of the abdomen with iodinated contrast within 2 weeks. Exclusion Criteria: - Persons with contraindication to iodinated contrast - Allergy to iodinated contrast - Renal insufficiency (serum creatinine > 1.5 mg/dl) - Patients with contraindication to ionizing radiation - Pregnancy - Patients with previous pancreatic surgery - Contraindication to secretin - Allergy to secretin - Acute pancreatitis


NCT ID:

NCT00587132


Primary Contact:

Principal Investigator
Naoki Takahashi, M.D.
Mayo Clinic


Backup Contact:

N/A


Location Contact:

Rochester, Minnesota 55905
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

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