Expired Study
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Rochester, Minnesota 55905


Purpose:

It is our objective to improve the performance of CTC in the prepared colon, and to validate CTC in the unprepared colon for the detection of colorectal neoplasia. The cost-effectiveness ratio of CTC in the unprepared colon will compare favorably with other colorectal screening test.


Study summary:

To improve the diagnostic performance of CTC in the prepared colon using improved spatial resolution, advanced image displays, and computer-assisted diagnosis, and to optimize diagnostic performance of CTC in the unprepared colon for colorectal polyp detection using electronic stool subtraction and computer-aided diagnostic techniques. To estimate the sensitivity and specificity of CTC in the unprepared colon for clinically important colorectal neoplasms (large adenomas ≥ 1 cm) and to compare such estimates with colonoscopy. To survey patient acceptance of CTC in the unprepared colon, and to assess implications for health care costs and cost-effectiveness of CTC in the unprepared colon in comparison with other approaches.


Criteria:

Inclusion Criteria: Average risk or higher for colorectal cancer and scheduled for colonoscopy with any of the following indications: - Prior colorectal cancer, prior colorectal adenoma, strong family history of colorectal neoplasia, iron deficiency. - Age ≥ 40 -100 years - Known or highly suspected primary colorectal neoplasms > 10 mm (n = 160) - Higher than average risk for colorectal cancer and scheduled for colonoscopy with any of the following indications: prior colorectal cancer, prior colorectal adenoma, strong family history of colorectal neoplasia, iron deficiency. Exclusion Criteria: - Less than 1/2 of colorectum remaining - Inflammatory bowel disease (Crohns, Chronic Ulcerative Colitis) - Familial Polyposis - Melena, hematochezia


NCT ID:

NCT00586053


Primary Contact:

Principal Investigator
C. Daniel Johnson, M.D.
Mayo Clinic


Backup Contact:

N/A


Location Contact:

Rochester, Minnesota 55905
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 16, 2018

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