Expired Study
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Sacramento, California 95817


Purpose:

The purpose of this study is to determine the efficacy of the Definity (perflutren lipid microsphere Injectable Suspension) ultrasound contrast agent in identifying small tumors (hepatomas & metastases) within the liver. Primary objective: To estimate the increase in conspicuity of small intrahepatic tumors with contrast-enhanced sonography Secondary Objectives: To estimate the effect of tumor type, size, location and depth on the conspicuity of small tumors on contrast-enhanced sonography


Study summary:

An estimated 75 patients (age 18 years of age or older) will be enrolled from the population of patients who present for ultrasound-guided radiofrequency ablation (RFA) of CT or MRI-confirmed multiple primary hepatocellular carcinoma (HCC) or metastatic carcinoma, with at least one of the tumors being ≤ 1.5 cm in diameter.


Criteria:

Inclusion Criteria: - Patients with primary hepatocellular carcinoma (HCC) or secondary (metastatic) carcinoma of the liver who have been referred for ultrasound-guided radiofrequency ablation (RFA) treatment - Recent (within 90 days) CT or MRI scan with report of one or more tumors ≤ 1.5 cm in diameter - Patient is stable and is to be managed conservatively (i.e. non-surgically) - 18 years of age or older - Ability and willingness to provide written informed consent Exclusion Criteria: - Known or suspected cardiac shunt(s) - Known sensitivity to octafluoropropane - Pregnant or breastfeeding


NCT ID:

NCT00584402


Primary Contact:

Principal Investigator
John P. McGahan, M.D.
UC Davis School of Medicine Dept. of Radiology


Backup Contact:

N/A


Location Contact:

Sacramento, California 95817
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2018

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