Galveston, Texas 77555


Purpose:

The purpose of this study is to evaluate the presence of cough reflex in the transplanted lung of patients who have had either a single or double lung transplant or heart-lung transplant at University of Texas Medical Branch. At the 1 year post transplant bronchoscopy, the presence of the cough reflex will be assessed by placing 3 to 5 ml of 5% dextrose (sugar water) or mechanical stimulation with standard bronchial biopsy forceps in three separate areas of the transplanted lung(s). The cough reflex will be assessed by recording the surface electrical activity by placing external electrodes to monitor the movement of abdominal muscles during a cough. The data will be recorded and compared with recordings from coughs recorded using the surface electrical activity of a cough generated by non-transplant patients.


Criteria:

Inclusion Criteria: - Lung transplant recipient - Hemodynamically stable - Capable of undergoing bronchoscopy Exclusion Criteria: - Pneumonia - Hypoxemia (PaO2 < 70) - Hemodynamic instability - Coagulopathy - Thrombocytopenia


NCT ID:

NCT00584077


Primary Contact:

Principal Investigator
Alexander G Duarte, MD
University of Texas

Alexander G Duarte, MD
Phone: 409-772-2436
Email: aduarte@utmb.edu


Backup Contact:

N/A


Location Contact:

Galveston, Texas 77555
United States

Alexander G Duarte, MD
Phone: 409-772-2436
Email: aduarte@utmb.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: March 16, 2018

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